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1,000 Women Over 5 Years

Choose your profile to see what the research actually says — in absolute numbers, not percentages.

Age group
Most large studies included predominantly women aged 50+. These figures use the 45–49 data as the closest reference. Your baseline risks are likely even lower — treat these as a conservative starting point for your conversation.
Type of MHT
Delivery route

1,000 women over 5 years — Breast cancer

No event
Affected without MHT
Extra with MHT
Outcome Without MHT With MHT Difference
For women with moderate to severe symptoms, MHT is the most effective treatment available for hot flashes, night sweats, sleep disruption, and mood changes. These benefits typically appear within weeks. No per-thousand statistic captures what it feels like to sleep through the night again — but that's often the reason women start, and the reason they stay.

These are population averages from large studies. Your individual risk depends on factors this calculator doesn't capture — your genetics, lifestyle, and overall health. Print this page and bring it to your next appointment.